Adam P Dicker Selected Research

1- (2- hydroxy- 2- methylpropyl)- N- (5- (7- methoxyquinolin- 4- yloxy)pyridin- 2- yl)- 5- methyl- 3- oxo- 2- phenyl- 2,3- dihydro- 1H- pyrazole- 4- carboxamide

11/2012

Higher levels of c-Met expression and phosphorylation identify cell lines with increased sensitivity to AMG-458, a novel selective c-Met inhibitor with radiosensitizing effects.

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Adam P Dicker Research Topics

Disease

81	Neoplasms (Cancer) 01/2022 - 03/2003
68	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2003
16	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2007
9	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2005
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 07/2012
8	Lung Neoplasms (Lung Cancer) 12/2020 - 10/2013
7	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/2013 - 01/2007
6	Disease Progression 12/2018 - 12/2012
6	Glioma (Gliomas) 05/2016 - 06/2010
5	Adenocarcinoma 11/2016 - 02/2003
4	Carcinoma (Carcinomatosis) 11/2017 - 01/2009
3	Pain (Aches) 01/2022 - 08/2003
3	Brain Neoplasms (Brain Tumor) 01/2021 - 01/2017
3	Hemorrhage 01/2020 - 02/2003
3	Melanoma (Melanoma, Malignant) 01/2017 - 01/2014
3	Margins of Excision 11/2016 - 12/2014
3	Meningioma (Meningiomas) 09/2012 - 08/2003
2	Fatigue 01/2022 - 10/2014
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2020 - 09/2016
2	Breast Neoplasms (Breast Cancer) 11/2018 - 01/2013
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2018 - 01/2007
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 01/2009
2	Cardiotoxicity 01/2018 - 12/2011
2	Extranodal Extension 11/2016 - 12/2014
2	Erectile Dysfunction 03/2015 - 01/2015
2	Urinary Incontinence 03/2015 - 08/2004
2	Retinoblastoma (Glioblastoma, Retinal) 11/2014 - 01/2005
2	Necrosis 04/2014 - 01/2005
2	Hypoxia (Hypoxemia) 01/2014 - 01/2005
2	Colorectal Neoplasms (Colorectal Cancer) 10/2013 - 11/2009
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2009 - 05/2006
1	Cytokine Release Syndrome 01/2021
1	Fever (Fevers) 01/2021

Drug/Important Bio-Agent (IBA)

15	Biomarkers (Surrogate Marker)IBA 01/2020 - 06/2004
11	Prostate-Specific Antigen (Semenogelase)IBA 01/2018 - 06/2004
8	AndrogensIBA 01/2020 - 01/2012
8	ErbB Receptors (EGF Receptor)IBA 11/2017 - 08/2003
7	Hormones (Hormone)IBA 01/2021 - 01/2003
7	Proteins (Proteins, Gene)FDA Link 01/2018 - 04/2004
6	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2018
6	Temozolomide (Temodar)FDA LinkGeneric 01/2021 - 06/2009
6	Biological ProductsIBA 01/2018 - 10/2008
5	Androgen Receptors (Androgen Receptor)IBA 11/2019 - 02/2012
5	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 01/2007
5	Celecoxib (Celebrex)FDA Link 01/2013 - 08/2003
4	Docetaxel (Taxotere)FDA Link 11/2019 - 03/2003
4	DNA (Deoxyribonucleic Acid)IBA 12/2018 - 01/2013
4	Fluorouracil (Carac)FDA LinkGeneric 01/2018 - 01/2007
4	Pharmaceutical PreparationsIBA 01/2018 - 04/2007
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2014 - 08/2003
3	pembrolizumabIBA 12/2020 - 09/2016
3	IntegrinsIBA 04/2019 - 07/2013
3	Androgen Antagonists (Antiandrogens)IBA 01/2018 - 01/2003
3	Cetuximab (Erbitux)FDA Link 11/2017 - 05/2012
3	Sunitinib (Sutent)FDA Link 10/2014 - 12/2011
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2014 - 04/2007
3	Tyrosine Kinase InhibitorsIBA 05/2013 - 01/2012
3	Bortezomib (Velcade)FDA Link 07/2012 - 01/2009
3	Proteasome InhibitorsIBA 07/2012 - 01/2009
2	RNA (Ribonucleic Acid)IBA 01/2021 - 12/2014
2	Transaminases (Aminotransferases)IBA 01/2020 - 10/2014
2	cabazitaxel FDA Link 01/2020 - 02/2015
2	PlatinumIBA 11/2019 - 01/2018
2	Radium-223IBA 01/2018 - 08/2017
2	Cytostatic AgentsIBA 01/2018 - 02/2015
2	Panitumumab (Vectibix)FDA Link 01/2017 - 10/2013
2	Monoclonal AntibodiesIBA 09/2016 - 05/2012
2	Taxoids (Taxanes)IBA 02/2015 - 03/2003
2	MicroRNAs (MicroRNA)IBA 01/2014 - 01/2014
2	afliberceptIBA 01/2014 - 04/2007
2	Growth Factor ReceptorsIBA 10/2013 - 01/2012
2	Gefitinib (Iressa)FDA Link 04/2013 - 12/2011
2	Sorafenib (BAY 43-9006)FDA Link 02/2013 - 12/2011
2	epidermal growth factor receptor VIIIIBA 01/2013 - 11/2011
2	Transcription Factors (Transcription Factor)IBA 12/2012 - 01/2009
2	cediranib (AZD2171)IBA 01/2012 - 11/2011
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2012 - 04/2007
2	vandetanib (ZD6474)IBA 01/2012 - 11/2009
2	Angiogenesis InhibitorsIBA 12/2011 - 06/2003
2	NF-kappa B (NF-kB)IBA 01/2009 - 05/2006
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 08/2003 - 08/2003
2	Paclitaxel (Taxol)FDA LinkGeneric 06/2003 - 03/2003
1	Blood Proteins (Serum Proteins)IBA 01/2022
1	Analgesics (Analgesic Drugs)IBA 01/2022
1	BRCA1 ProteinIBA 01/2021
1	Chimeric Antigen ReceptorsIBA 01/2021

Therapy/Procedure

85	Radiotherapy 01/2020 - 02/2003
43	Therapeutics 01/2022 - 01/2003
23	Prostatectomy (Retropubic Prostatectomy) 01/2021 - 04/2011
16	Brachytherapy 05/2020 - 07/2002
9	Chemoradiotherapy 01/2017 - 09/2007
8	Drug Therapy (Chemotherapy) 01/2020 - 06/2009
5	Aftercare (After-Treatment) 01/2020 - 02/2013
5	Castration 11/2019 - 12/2012
4	Immunotherapy 01/2021 - 09/2016
3	Re-Irradiation 05/2016 - 06/2010
2	Pain Management 01/2022 - 01/2022
2	Conformal Radiotherapy 10/2013 - 10/2008
2	Radiation Dosimeters 03/2013 - 07/2012
1	Wearable Electronic Devices 01/2021